Target with-in target

Aiming to break therapeutic mediocrity

Keywords: Molecular imaging, Molecular target, Pharmaco-therapeutics, Receptors, Target exposure

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Author Biography

Mohammed Abdul Hannan Hazari, Deccan College of Medical Sciences

Professor & Head, Department of Physiology

References


  1. Bremer C. Molecular targets. In: Baert AL (ed) Encyclopedia of Diagnostic Imaging. New York: Springer Berlin Heidelberg, pp.1154-55, 2008.

  2. Society of Nuclear Medicine and Molecular Imaging. What are molecular imaging and nuclear medicine? Available from: http://www.snmmi.org/AboutSNMMI/Content.aspx?ItemNumber=6433 [Last accessed August 16, 2017]

  3. Molecular imaging. Available from: https://en.wikipedia.org/wiki/Molecular_imaging (Last accessed August 16, 2017)

  4. Verdine GL, Hilinski GJ. Stapled peptides for intracellular drug targets. Methods Enzymol. 2012; 503:3-33. [Pubmed] [Crossref]

  5. Imming P, Sinning C, Meyer A. Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct; 5(10):821-34. [Pubmed] [Crossref]

  6. Eleven Biotherapeutics. Vicinium™ (VB4-845): Recombinant fusion protein in clinical development for the treatment of high-grade non-muscle invasive bladder cancer. Available from: http://www.elevenbio.com/pipeline/vicinium.html (Last accessed August 21, 2017)

  7. Cardinale A, Biocca S. The potential of intracellular antibodies for therapeutic targeting of protein-misfolding diseases. Trends Mol Med. 2008 Sep; 14(9):373-80. [Pubmed] [Crossref]

  8. Reverdatto S, Burz DS, Shekhtman A. Peptide aptamers: development and applications. Curr Top Med Chem. 2015; 15(12):1082-101. [Pubmed] [Crossref]

  9. Mateus A, Gordon LJ, Wayne GJ, Almqvist H, Axelsson H, Seashore-Ludlow B, Treyer A, Matsson P, Lundbäck T, West A, Hann MM, Artursson P. Prediction of intracellular exposure bridges the gap between target- and cell-based drug discovery. Proc Natl Acad Sci U S A. 2017 Jul 25; 114(30):E6231-E6239. [Pubmed] [Crossref]


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Published
2018-03-31
How to Cite
1.
Hazari M. Target with-in target. Quench Academy of Medical Education and Research Annals of Medical Physiology [Internet]. 31Mar.2018 [cited 17Aug.2018];2(1):1-. Available from: http://amphysiol.com/index.php/amp/article/view/v2i1.275951
Section
Editorial

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