Annals of Medical Physiology https://amphysiol.com/index.php/amp <p><strong><span style="margin: 0px; line-height: 150%; font-family: 'Arial','sans-serif'; font-size: 12pt;">Annals of Medical Physiology</span></strong><span style="margin: 0px; line-height: 150%; font-family: 'Arial','sans-serif'; font-size: 12pt;"> (<em>Ann Med Physiol.</em>) is a double-blind peer-reviewed quarterly journal, published online, aims to provide the most complete and reliable source of information on current developments in the field of medical physiology. The emphasis will be on publishing quality research papers rapidly and keep freely available to researchers worldwide through </span><a title="Open Access Policy" href="https://amphysiol.com/amp/oa" target="_blank" rel="noopener"><span style="margin: 0px; line-height: 150%; font-family: 'Arial','sans-serif'; font-size: 12pt;"><span style="color: #0000ff;">open access policy</span></span></a><span style="margin: 0px; line-height: 150%; font-family: 'Arial','sans-serif'; font-size: 12pt;">. All articles are freely available without charge to the user or his/her institution. Users are allowed to read, download, copy, distribute, print, search, or link to the full texts of the articles, or use them for any other lawful purpose, without asking prior permission from the publisher or the author. <br /></span></p> <p><span style="margin: 0px; line-height: 150%; font-family: 'Arial','sans-serif'; font-size: 12pt;"> <strong>Annals of Medical Physiology</strong> serves an important role by encouraging, fostering and promoting developments in various areas of medical physiology. This journal publishes reviews, original research articles, brief communications in all areas of medical physiology.</span></p> <p><strong><span style="margin: 0px; line-height: 150%; font-family: 'Arial','sans-serif'; font-size: 12pt;">Features:</span></strong></p> <ul type="disc"> <li class="show" style="margin: 0px 0px 8px; color: #000000; line-height: 150%; font-family: 'Arial','sans-serif'; font-size: 12pt; font-style: normal; font-weight: normal;"><span style="margin: 0px; line-height: 150%; font-family: 'Arial','sans-serif'; font-size: 12pt;">International quality</span></li> <li class="show" style="margin: 0px 0px 8px; color: #000000; line-height: 150%; font-family: 'Arial','sans-serif'; font-size: 12pt; font-style: normal; font-weight: normal;"><span style="margin: 0px; line-height: 150%; font-family: 'Arial','sans-serif'; font-size: 12pt;">Published quarterly (Jan-Mar, Apr-June, July-Sept, Oct-Dec)</span></li> <li class="show" style="margin: 0px 0px 8px; color: #000000; line-height: 150%; font-family: 'Arial','sans-serif'; font-size: 12pt; font-style: normal; font-weight: normal;"><span style="margin: 0px; line-height: 150%; font-family: 'Arial','sans-serif'; font-size: 12pt;">Online manuscript submission</span></li> <li class="show" style="margin: 0px 0px 8px; color: #000000; line-height: 150%; font-family: 'Arial','sans-serif'; font-size: 12pt; font-style: normal; font-weight: normal;"><span style="margin: 0px; line-height: 115%; font-family: 'Arial','sans-serif'; font-size: 12pt;">Nominal publication charges</span></li> </ul> en-US <p>The authors warrants and represents that the submitted <strong>MANUSCRIPT</strong> is an original work and has not been published before in any form, and that it does not infringe upon any copyright or other right(s), that it does not contain infringing, libelous, obscene or other unlawful matter, that he/she is the sole and exclusive owner of the rights here-in conveyed to the Publisher, and that he/she has obtained the customary permission from the copyright owner or his legal representative whenever a text/passage from copyrighted material is quoted or a table or illustration from such material is used. The Author(s) will indemnify the Publisher for, and hold the Publisher harmless from any loss, expense or damage occasioned by any claim or suit by a third party for copyright infringement or arising out of any breach of the foregoing warranties as a result of publication of the Article. The Article shall be delivered to the Publisher free of copyright charges. In the event that the Article is not accepted and published by Publisher, this agreement becomes null and void.</p> <p>Sherpa/Romeo publisher policy can be viewed at <a title="Sherpa/Romeo" href="https://v2.sherpa.ac.uk/id/publication/37748" target="_blank" rel="noopener">Annals of Medical Physiology - Sherpa/Romeo Policy</a></p> editor@amphysiol.com (Dr. Mohammed Abdul Hannan Hazari) hannanhazari@qamer.org (Dr. Mohammed Abdul Hannan Hazari) Fri, 12 Aug 2022 00:00:00 +0530 OJS 3.2.1.2 http://blogs.law.harvard.edu/tech/rss 60 asdasddsa asdasdasd https://amphysiol.com/index.php/amp/article/view/64 <p>asdasdsda</p> atengg377 saepudin Copyright (c) https://amphysiol.com/index.php/amp/article/view/64 Caffeine and Camellia sinensis enhance cognition and increased acetylcholinesterase activity in scopolamine-induced memory loss in female Swiss mice. https://amphysiol.com/index.php/amp/article/view/62 <p>Caffeine and&nbsp;<em>Camellia sinensis</em> (green tea) has been known to have positive effect on memory. The present study investigated the possible effect of caffeine and green tea co-administration on oxidative stress markers, inflammatory marker and acetylcholinesterase activity in scopolamine-induced memory loss in female Swiss mice.&nbsp;</p> <p>Memory behavioral tests using Y-maze and Morris water maze was carried out, followed by oxidative stress biomarkers, acetylcholinesterase activity and Tumor Necrosis Factor (TNF) alpha evaluation from the mice brain tissues after caffeine and green tea administration.&nbsp;</p> <p>Scopolamine administered intraperitoneally at a dose of 1mg/kg BW for 7 days significantly reduced the percent alternation of the mice in Y-maze thus, increased acetylcholinesterase activity and increased TNF alpha level. However, caffeine administered orally at a dose 50mg/kg BW and green tea administered orally at a dose of 60mg/kg BW increased the percent alternation significantly, increased the percent alternation, reduced acetylcholine esterase activity and reduced the TNF alpha level significantly. However oxidative stress markers evaluated GSH and MDA, showed no significant difference across all groups.</p> <p>These findings showed scopolamine has a deteriorating effect on cognition by increasing acetylcholinesterase activities thus mopping out acetylcholine at a faster rate. However, caffeine and green tea singly and in combination restored cognition, reduced acetylcholinesterase activity and restored TNF alpha level. The neuroprotective effect of caffeine and green tea was compared to that of Donepezil, an established cognition enhancing drug and the effect was agonistic.&nbsp;The ability of caffeine and green tea to reduce acetylcholinesterase activity could be the mechanism for the ability to enhance memory. The ability of these compounds in restoring TNF alpha level also further potentiates their neuroprotective capability.</p> Dr. Aminat Omolola Imam-Fulani, Miss, Oluwajuwonlo Justina Ogungbemi, Lateefat Omotoyosi Olajide, Tayyib Adekunle Adedeji, Maryam Abidemi Ibrahim, Emmanuel Emaikwu, Fatima Ayinla, . Adedamola Adediran Fafure, Lekan Sheriff Ojulari Copyright (c) https://amphysiol.com/index.php/amp/article/view/62 Situs Slot Deposit Dana Tanpa Potongan https://amphysiol.com/index.php/amp/article/view/63 <p>Situs slot deposit dana tanpa potongan banyak bonus buat member baru ataupun lama.</p> slotdana Copyright (c) https://amphysiol.com/index.php/amp/article/view/63 Assessing the effects of Instagram and WhatsApp use on behavior of population in south west region of Saudi Arabia https://amphysiol.com/index.php/amp/article/view/v6i1.00059 <p>Social media not only have been proven to cause unhappiness, but it can also lead to development of mental health issues like stress or depression when used too much or without caution. The present study was aimed to assess the knowledge, attitude and behavior of the individuals regarding consequences of Instagram and WhatsApp usage on mental health. The web link of the online questionnaire was disseminated and data was collected for 15 days (16<sup>th</sup> to 30<sup>th</sup> January 2022). A total of 632 participants gave consent and took part in this survey. Majority of the participants (76.3%) don't think that WhatsApp use can violate their privacy but 54.6% users have knowledge regarding its negative effects on health and lifestyle. Interestingly, 57% participant refuses to stop using WhatsApp even after knowing the negative effects. Majority of respondents reported that they didn't get influenced about the “stuff” on Instagram. However, 31.80% participants accepted that their feelings get influenced by the number of "likes" they get, and 44.4% participant stated that Instagram have effect on their mood and 19.3% respondents reported that they feel pressure to fit into a certain image on social media. Even, 21.2% participants accepted that they face mental issues because of Instagram use. A small proportion of Instagram users in Jazan reported that it has negative impact on mental health. Majority of the participants are not willing to stop use of WhatsApp even after knowing the adverse effects. It is advisable for social media users to create a social-media free slot in daily routine if they feel sad, lonely or depressed after using social media apps.</p> Farrukh Sobia, Shahazad Niwazi Qurashi, Karunamoorthi Annamalai, Tohani Babiker Mohamed, Faiza kheiry Copyright (c) 2022 Quench Academy of Medical Education and Research (QAMER) https://creativecommons.org/licenses/by/4.0 https://amphysiol.com/index.php/amp/article/view/v6i1.00059 Fri, 12 Aug 2022 00:00:00 +0530 Evaluation and comparison of Sympathetic Autonomic Function between Hypertensive and Normotensive Subjects https://amphysiol.com/index.php/amp/article/view/56 <p><strong>Objectives: </strong>To identify the differences of sympathetic autonomic function between hypertensive and normotensive individuals. <strong>Methods: </strong>A CASE and a CONTROL group each constituting with a sample of 44 subjects between the age group 25-65 years were recruited in the study. Autonomic function assessments were conducted with the help of Isometric Handgrip Test and Orthostatic Blood Pressure Test. Data were statistically analyzed using SPSS (Version 20.0). Descriptive statistics was presented as frequencies, percentages and mean± S.D. Statistical differences between the parameters of case and control groups were conducted by Mann- Whitney U-test and Paired T-test. P&lt;0.05 was statistically significant. <strong>Results: </strong>Majority (54.5%) of the hypertensive patients belonged to the age group of 56-65 years. The mean difference in DBP after the Isometric Hand grip test in case group were not found to be higher than even 5 mmHg but, in the control group were greater than 15 mmHg with differences recorded among the groups being highly statistically significant (P=0.00). The mean SBP and DBP differences (after Orthostatic BP test) between lying down and sitting postures in both the cases and controls were found to be statistically significant with P values: 0.02, 0.02, 0.002 and 0.002 respectively. <strong>Conclusions: </strong>Hypertensive cases recruited for the study had impaired autonomic function when compared to the normotensive controls of the same age- group (25-65years).&nbsp;</p> Radhika, Roopasree Copyright (c) https://amphysiol.com/index.php/amp/article/view/56 Article review: Present Perspectives of Hyperthyroidism during Pregnancy https://amphysiol.com/index.php/amp/article/view/54 <p><strong>Abstract:</strong></p> <p>Graves' disease causes inflammatory hyperthyroidism in around 80% of hyperthyroidism cases in women of reproductive age. The hormonal changes in the maternal immune system after birth may be linked to the production and expression of diabetes other than gestational and early-onset diabetes. As a result, in addition to hormonal influences, other anatomical modifications or abnormalities seen in the body during pregnancy will affect the pregnancy test. Thyroid hormones are critical for a woman's health and the commencement of her pregnancy. These hormones are essential for early development and play a crucial role in the fetus's continued growth after conception. Women with untreated or improperly controlled hyperthyroidism are more likely to have complications during pregnancy. Future diseases, particularly those that produce a large number of fetuses due to IUGRTH. The treatment of hyperthyroid pregnant women is extremely difficult, and medical staff engagement is required to guarantee that it is properly monitored and treated. Anti-thyroid drugs are commonly administered to pregnant women, and it is the medication of choice for the majority of them (ATDs). Despite the fact that both of these drugs are passed through the mother's bloodstream to the fetus, they are highly effective in the treatment of maternal hyperthyroidism. Nonetheless, they must exercise caution throughout the second half of pregnancy due to the risk of fetopathy. The most common side effect, except in the first trimesters from weeks 6 to 10, is fetal abnormalities; even with that proviso, the incidence of birth malformations is significant during the first trimester with the use of ATDs. The management of hyperthyroidism during pregnancy is divided into four areas that obstetricians are currently concerned about: Its aetiology, occurrence, correct identification, under treatment, complications, and actual or missed diagnosis and intervention, and lastly, the technique of dealing with the problem are all factors to consider.</p> meena Copyright (c) https://amphysiol.com/index.php/amp/article/view/54 Hormonal and Hematological Imbalance and Female Infertility https://amphysiol.com/index.php/amp/article/view/53 <p>Poly cystic ovary synrdome (PCOS) is a common endocrinological disorder among women of the reproductive stage. The current study was conducted to evaluate some hormonal and hematological alterations in patients with poly cystic ovarian syndrome(PCOS), BMI or the body mass index was determined for all women, serum hormones (SHBG), Estradiol ,DHEAs , Leptin ,Inhibin-B, were measured, and hematological changes include PAI-1 activity, fibrinogen and t-PA antigen also measured. The results of the present study showed, there were significant increase (p&lt;0.05) in BM, DHEAs<strong>, </strong>Leptin , Inhibin-B , PAI-1 ,fibrinogen and t-PA antigen in PCOS women compared with the control group, but asignificant decrease&nbsp; (p&gt;0.05) in SHBG and E<sub>2</sub> .</p> meena Copyright (c) https://amphysiol.com/index.php/amp/article/view/53 Effect of aspirin administration on body weight and liver enzymes in male rats https://amphysiol.com/index.php/amp/article/view/v5i3.00051 <p>The present study was conducted to evaluate the effects of aspirin on body weight and some liver enzyme in rats. The study was done in Veterinary Medicine College, Baghdad University. We used seventy two male rats and randomly divided into three groups (24 in each group). Group-1 was considered as control, Group-2 animals were treated by 40 mg/kg body weight (low-dose) of asprin and the Group-3 was treated by 100 mg/kg body weight (high-dose) of aspirin. The results showed no significant difference in bodyweight gain from 0 to 10 days in all groups, while the low and high-dose asprin treated rats showed decline in bodyweight gain on day 20 and day 30 of aspirin treatment. The liver enzymes, AST and ALT, increased significantly in high-dose of aspirin treated group on day 20 and 30 while the ALP was increased on all time-points in high-dose asprin treated group.</p> Faraj Hato Johni Al-Bidhani Copyright (c) 2021 Quench Academy of Medical Education and Research (QAMER) https://creativecommons.org/licenses/by/4.0 https://amphysiol.com/index.php/amp/article/view/v5i3.00051 Fri, 31 Dec 2021 00:00:00 +0530 A Correlation Study of some socio-demographic factors, gender, age, body mass index and some cardiovascular parameters of hypertensive subjects in Yenagoa, Bayelsa state, Nigeria. https://amphysiol.com/index.php/amp/article/view/49 <p>Hypertension is defined as a sustained elevated arterial pressure to a level that places the patient at increased risk of organ damage.&nbsp; It is a non-communicable disease which constitutes a public health importance. Its risk factors include age, high salt intake, excessive alcohol consumption and stress. This study was performed to determine the correlation between some socio-demographic factors, Gender, Age, Body Mass Index and some cardiovascular parameters of Hypertensive patients in Yenagoa, Bayelsa State, Nigeria.The study was carried out with 400 hypertensive subjects, whose blood pressures were determined using palpatory and auscultatory methods. The Gender, Age and Body Mass Index of the subjects were also determined. Statistical analysis was done using Z-statistics. There was found a significant positive relationship between the age and cardiovascular parameters. Gender and BMI were found to have an insignificant positive correlation with the cardiovascular parameters. The study demonstrated that body mass index, age and gender are closely associated with cardiovascular parameters, though the degree of correlation differed. The risk of hypertension is therefore expected to be higher among the aged and populations who are overweight or obese.</p> Sunday Ojeka Copyright (c) https://amphysiol.com/index.php/amp/article/view/49 Correlation study of socio-demographic factors like gender, age, body mass index and some cardiovascular parameters in hypertensive subjects of Yenagoa, Bayelsa state, Nigeria https://amphysiol.com/index.php/amp/article/view/v5i2.00046 <p>Hypertension is defined as a sustained elevated arterial pressure to a level that places the patient at increased risk of organ damage. It is a non-communicable disease which constitutes a public health importance. Its risk factors include advancing age, high salt intake, excessive alcohol consumption and stress. This study was performed to determine the correlation between some socio-demographic factors like gender, age, body mass index (BMI) and some cardiovascular parameters in hypertensive patients of Yenagoa, Bayelsa State, Nigeria. The study was carried out with 400 hypertensive subjects, whose blood pressures were determined using palpatory and auscultatory methods. The gender, age and body mass index of the subjects were also determined. Statistical analysis was done using Z-statistics. We found a significant positive relationship between the age and cardiovascular parameters. Gender and BMI were found to have an insignificant positive correlation with the cardiovascular parameters. The study demonstrated that body mass index, age and gender are closely associated with cardiovascular parameters, though the degree of correlation differed. The risk of hypertension is therefore expected to be higher among the aged and populations who are overweight or obese.</p> Ayebatonbra Egbejimi Michael, Sunday Ogbu Ojeka, Zigabelbari Zabbey Victor Copyright (c) 2021 Quench Academy of Medical Education and Research (QAMER) https://creativecommons.org/licenses/by/4.0 https://amphysiol.com/index.php/amp/article/view/v5i2.00046 Sat, 20 Nov 2021 00:00:00 +0530