Annals of Medical Physiology https://amphysiol.com/index.php/amp <p><strong><span style="margin: 0px; line-height: 150%; font-family: 'Arial','sans-serif'; font-size: 12pt;">Annals of Medical Physiology</span></strong><span style="margin: 0px; line-height: 150%; font-family: 'Arial','sans-serif'; font-size: 12pt;"> (<em>Ann Med Physiol.</em>) is a double-blind peer-reviewed quarterly journal, published online, aims to provide the most complete and reliable source of information on current developments in the field of medical physiology. The emphasis will be on publishing quality research papers rapidly and keep freely available to researchers worldwide through </span><a title="Open Access Policy" href="https://amphysiol.com/amp/oa" target="_blank" rel="noopener"><span style="margin: 0px; line-height: 150%; font-family: 'Arial','sans-serif'; font-size: 12pt;"><span style="color: #0000ff;">open access policy</span></span></a><span style="margin: 0px; line-height: 150%; font-family: 'Arial','sans-serif'; font-size: 12pt;">. All articles are freely available without charge to the user or his/her institution. Users are allowed to read, download, copy, distribute, print, search, or link to the full texts of the articles, or use them for any other lawful purpose, without asking prior permission from the publisher or the author. <br /></span></p> <p><span style="margin: 0px; line-height: 150%; font-family: 'Arial','sans-serif'; font-size: 12pt;"> <strong>Annals of Medical Physiology</strong> serves an important role by encouraging, fostering and promoting developments in various areas of medical physiology. This journal publishes reviews, original research articles, brief communications in all areas of medical physiology.</span></p> <p><strong><span style="margin: 0px; line-height: 150%; font-family: 'Arial','sans-serif'; font-size: 12pt;">Features:</span></strong></p> <ul type="disc"> <li class="show" style="margin: 0px 0px 8px; color: #000000; line-height: 150%; font-family: 'Arial','sans-serif'; font-size: 12pt; font-style: normal; font-weight: normal;"><span style="margin: 0px; line-height: 150%; font-family: 'Arial','sans-serif'; font-size: 12pt;">International quality</span></li> <li class="show" style="margin: 0px 0px 8px; color: #000000; line-height: 150%; font-family: 'Arial','sans-serif'; font-size: 12pt; font-style: normal; font-weight: normal;"><span style="margin: 0px; line-height: 150%; font-family: 'Arial','sans-serif'; font-size: 12pt;">Published quarterly (Jan-Mar, Apr-June, July-Sept, Oct-Dec)</span></li> <li class="show" style="margin: 0px 0px 8px; color: #000000; line-height: 150%; font-family: 'Arial','sans-serif'; font-size: 12pt; font-style: normal; font-weight: normal;"><span style="margin: 0px; line-height: 150%; font-family: 'Arial','sans-serif'; font-size: 12pt;">Online manuscript submission</span></li> <li class="show" style="margin: 0px 0px 8px; color: #000000; line-height: 150%; font-family: 'Arial','sans-serif'; font-size: 12pt; font-style: normal; font-weight: normal;"><span style="margin: 0px; line-height: 115%; font-family: 'Arial','sans-serif'; font-size: 12pt;">Nominal publication charges</span></li> </ul> Quench Academy of Medical Education and Research (QAMER) Publishing House en-US Annals of Medical Physiology 2456-8422 <p>The authors warrants and represents that the submitted <strong>MANUSCRIPT</strong> is an original work and has not been published before in any form, and that it does not infringe upon any copyright or other right(s), that it does not contain infringing, libelous, obscene or other unlawful matter, that he/she is the sole and exclusive owner of the rights here-in conveyed to the Publisher, and that he/she has obtained the customary permission from the copyright owner or his legal representative whenever a text/passage from copyrighted material is quoted or a table or illustration from such material is used. The Author(s) will indemnify the Publisher for, and hold the Publisher harmless from any loss, expense or damage occasioned by any claim or suit by a third party for copyright infringement or arising out of any breach of the foregoing warranties as a result of publication of the Article. The Article shall be delivered to the Publisher free of copyright charges. In the event that the Article is not accepted and published by Publisher, this agreement becomes null and void.</p> <p>Sherpa/Romeo publisher policy can be viewed at <a title="Sherpa/Romeo" href="https://v2.sherpa.ac.uk/id/publication/37748" target="_blank" rel="noopener">Annals of Medical Physiology - Sherpa/Romeo Policy</a></p> Evaluation and comparison of Sympathetic Autonomic Function between Hypertensive and Normotensive Subjects https://amphysiol.com/index.php/amp/article/view/56 <p><strong>Objectives: </strong>To identify the differences of sympathetic autonomic function between hypertensive and normotensive individuals. <strong>Methods: </strong>A CASE and a CONTROL group each constituting with a sample of 44 subjects between the age group 25-65 years were recruited in the study. Autonomic function assessments were conducted with the help of Isometric Handgrip Test and Orthostatic Blood Pressure Test. Data were statistically analyzed using SPSS (Version 20.0). Descriptive statistics was presented as frequencies, percentages and mean± S.D. Statistical differences between the parameters of case and control groups were conducted by Mann- Whitney U-test and Paired T-test. P&lt;0.05 was statistically significant. <strong>Results: </strong>Majority (54.5%) of the hypertensive patients belonged to the age group of 56-65 years. The mean difference in DBP after the Isometric Hand grip test in case group were not found to be higher than even 5 mmHg but, in the control group were greater than 15 mmHg with differences recorded among the groups being highly statistically significant (P=0.00). The mean SBP and DBP differences (after Orthostatic BP test) between lying down and sitting postures in both the cases and controls were found to be statistically significant with P values: 0.02, 0.02, 0.002 and 0.002 respectively. <strong>Conclusions: </strong>Hypertensive cases recruited for the study had impaired autonomic function when compared to the normotensive controls of the same age- group (25-65years).&nbsp;</p> Radhika P Roopasree B Copyright (c) 5 3 Article review: Present Perspectives of Hyperthyroidism during Pregnancy https://amphysiol.com/index.php/amp/article/view/54 <p><strong>Abstract:</strong></p> <p>Graves' disease causes inflammatory hyperthyroidism in around 80% of hyperthyroidism cases in women of reproductive age. The hormonal changes in the maternal immune system after birth may be linked to the production and expression of diabetes other than gestational and early-onset diabetes. As a result, in addition to hormonal influences, other anatomical modifications or abnormalities seen in the body during pregnancy will affect the pregnancy test. Thyroid hormones are critical for a woman's health and the commencement of her pregnancy. These hormones are essential for early development and play a crucial role in the fetus's continued growth after conception. Women with untreated or improperly controlled hyperthyroidism are more likely to have complications during pregnancy. Future diseases, particularly those that produce a large number of fetuses due to IUGRTH. The treatment of hyperthyroid pregnant women is extremely difficult, and medical staff engagement is required to guarantee that it is properly monitored and treated. Anti-thyroid drugs are commonly administered to pregnant women, and it is the medication of choice for the majority of them (ATDs). Despite the fact that both of these drugs are passed through the mother's bloodstream to the fetus, they are highly effective in the treatment of maternal hyperthyroidism. Nonetheless, they must exercise caution throughout the second half of pregnancy due to the risk of fetopathy. The most common side effect, except in the first trimesters from weeks 6 to 10, is fetal abnormalities; even with that proviso, the incidence of birth malformations is significant during the first trimester with the use of ATDs. The management of hyperthyroidism during pregnancy is divided into four areas that obstetricians are currently concerned about: Its aetiology, occurrence, correct identification, under treatment, complications, and actual or missed diagnosis and intervention, and lastly, the technique of dealing with the problem are all factors to consider.</p> meena Copyright (c) 5 3 Hormonal and Hematological Imbalance and Female Infertility https://amphysiol.com/index.php/amp/article/view/53 <p>Poly cystic ovary synrdome (PCOS) is a common endocrinological disorder among women of the reproductive stage. The current study was conducted to evaluate some hormonal and hematological alterations in patients with poly cystic ovarian syndrome(PCOS), BMI or the body mass index was determined for all women, serum hormones (SHBG), Estradiol ,DHEAs , Leptin ,Inhibin-B, were measured, and hematological changes include PAI-1 activity, fibrinogen and t-PA antigen also measured. The results of the present study showed, there were significant increase (p&lt;0.05) in BM, DHEAs<strong>, </strong>Leptin , Inhibin-B , PAI-1 ,fibrinogen and t-PA antigen in PCOS women compared with the control group, but asignificant decrease&nbsp; (p&gt;0.05) in SHBG and E<sub>2</sub> .</p> meena Copyright (c) 5 3 Effect of aspirin administration on body weight and liver enzymes in male rats https://amphysiol.com/index.php/amp/article/view/v5i3.00051 <p>The present study was conducted to evaluate the effects of aspirin on body weight and some liver enzyme in rats. The study was done in Veterinary Medicine College, Baghdad University. We used seventy two male rats and randomly divided into three groups (24 in each group). Group-1 was considered as control, Group-2 animals were treated by 40 mg/kg body weight (low-dose) of asprin and the Group-3 was treated by 100 mg/kg body weight (high-dose) of aspirin. The results showed no significant difference in bodyweight gain from 0 to 10 days in all groups, while the low and high-dose asprin treated rats showed decline in bodyweight gain on day 20 and day 30 of aspirin treatment. The liver enzymes, AST and ALT, increased significantly in high-dose of aspirin treated group on day 20 and 30 while the ALP was increased on all time-points in high-dose asprin treated group.</p> Faraj Hato Johni Al-Bidhani Copyright (c) 2021 Quench Academy of Medical Education and Research (QAMER) https://creativecommons.org/licenses/by/4.0 2021-12-31 2021-12-31 5 3 13 16 10.23921/amp.2021v5i3.00051 A Correlation Study of some socio-demographic factors, gender, age, body mass index and some cardiovascular parameters of hypertensive subjects in Yenagoa, Bayelsa state, Nigeria. https://amphysiol.com/index.php/amp/article/view/49 <p>Hypertension is defined as a sustained elevated arterial pressure to a level that places the patient at increased risk of organ damage.&nbsp; It is a non-communicable disease which constitutes a public health importance. Its risk factors include age, high salt intake, excessive alcohol consumption and stress. This study was performed to determine the correlation between some socio-demographic factors, Gender, Age, Body Mass Index and some cardiovascular parameters of Hypertensive patients in Yenagoa, Bayelsa State, Nigeria.The study was carried out with 400 hypertensive subjects, whose blood pressures were determined using palpatory and auscultatory methods. The Gender, Age and Body Mass Index of the subjects were also determined. Statistical analysis was done using Z-statistics. There was found a significant positive relationship between the age and cardiovascular parameters. Gender and BMI were found to have an insignificant positive correlation with the cardiovascular parameters. The study demonstrated that body mass index, age and gender are closely associated with cardiovascular parameters, though the degree of correlation differed. The risk of hypertension is therefore expected to be higher among the aged and populations who are overweight or obese.</p> Sunday Ojeka Copyright (c) 5 3 Correlation study of socio-demographic factors like gender, age, body mass index and some cardiovascular parameters in hypertensive subjects of Yenagoa, Bayelsa state, Nigeria https://amphysiol.com/index.php/amp/article/view/v5i2.00046 <p>Hypertension is defined as a sustained elevated arterial pressure to a level that places the patient at increased risk of organ damage. It is a non-communicable disease which constitutes a public health importance. Its risk factors include advancing age, high salt intake, excessive alcohol consumption and stress. This study was performed to determine the correlation between some socio-demographic factors like gender, age, body mass index (BMI) and some cardiovascular parameters in hypertensive patients of Yenagoa, Bayelsa State, Nigeria. The study was carried out with 400 hypertensive subjects, whose blood pressures were determined using palpatory and auscultatory methods. The gender, age and body mass index of the subjects were also determined. Statistical analysis was done using Z-statistics. We found a significant positive relationship between the age and cardiovascular parameters. Gender and BMI were found to have an insignificant positive correlation with the cardiovascular parameters. The study demonstrated that body mass index, age and gender are closely associated with cardiovascular parameters, though the degree of correlation differed. The risk of hypertension is therefore expected to be higher among the aged and populations who are overweight or obese.</p> Ayebatonbra Egbejimi Michael Sunday Ogbu Ojeka Zigabelbari Zabbey Victor Copyright (c) 2021 Quench Academy of Medical Education and Research (QAMER) https://creativecommons.org/licenses/by/4.0 2021-11-20 2021-11-20 5 3 7 12 10.23921/amp.2021v5i2.00046 Perception of data quality and electronic health information system acceptance, reliability and satisfaction: A study at tertiary care hospital in Saudi Arabia https://amphysiol.com/index.php/amp/article/view/v5i1.00044 <p>Electronic health information systems (EHIS) are considered a backbone for healthcare planning and quality services. This study was designed to explore the acceptance, reliability, and satisfaction of the end users' experience with the hospital electronic health information system. We also investigated the perception of data quality by the users who were directly involved in data entry. We conducted a questionnaire based cross-sectional survey to collect quantitative data from different EHIS users. The questionnaire contained six sections: demographic user information; general HIS assessment; accessibility and availability of computer terminals in the hospital; EHIS and the patient care; user satisfaction with the HIS and perception of data quality. Desktop computers were available throughout the hospital, but the hospital was lacking handheld computers or computers on wheels. Participants of the study were satisfied with the data entry and retrieval process but they were lacking job training related to troubleshooting. EHIS users were not aware and prepared for the downtime of the system and procedures were also not clear to them. Regarding the perception of data quality, most of the participants responded that data is of adequate quality. There is a need for proper technical support and enhance the hospital's networking speed for better response. Laptops and hand-held computers are the need of time for data entry in critical situations and during wards visit. This can also enhance the quality of data, and reduce the chances of data loss.</p> Asim Mehmood Abdu Mohammad Aqeeli Ali Musa Adulrahman Muhammad Osamah Muhammad Copyright (c) 2021 Quench Academy of Medical Education and Research (QAMER) https://creativecommons.org/licenses/by/4.0 2021-06-04 2021-06-04 5 3 1 6 10.23921/amp.2021v5i1.00044 How calyx juice of Hibiscus sabdariffa (Zobo) affects human platelet count https://amphysiol.com/index.php/amp/article/view/41 <p>“Zobo” is a popular local soft drink; made from the dried calyces of Hibiscus sabdariffa; widely consumed across towns, cities and cultures in Nigeria. A lot of health benefits have been attributed to this drink, some of which include anti-inflammatory, anti-diabetic, antihypertensive, hypocholesterolemic and antianemic effect. However, little is known on the effect of this refreshing drink on the human platelet count. Thus, this study was conducted to investigate the impact of the Calx juice of Hibiscus sabdariffa “Zobo” on the platelet level on young adult, who make up the demography that consume the drink a lot. For the purpose of this study, the researches employed the local method of preparing the “Zobo” drink and 50 (24 females and 26 males) subjects, randomly selected, voluntarily participated in the study. The study lasted for a period of 14 days and samples were collected from subjects before and after the 14th day of taking 500ml of “Zobo” drink. Platelet count was determined in collected samples and the data obtained analyzed with paired sample T-test using SPSS (version 20). The result shows that there is a significant decrease (p&lt;0.05) in the posttest (162.72 ± 0.428×109/l) when compared to the pretest was (262.7 ± 0.371×109/l) in male subjects. For the Female group, the result also shows that there is a significant decrease (p&lt;0.05) in the posttest (204.30 ± 0.583×109/l) when compared with the pretest (258.20 ± 0.472×109/l). Conclusion was therefore reached that juice made from the dried calyces of hibiscus sabdriffa reduces the platelet count of participants in this study.</p> Emmanuel Izuchukwu Orji Chukwudi Onyeka Okonkwo Lilian Obiageli Ozondu Copyright (c) 5 3 Evaluation of renal functions tests among Sudanese healthy pregnant women attending antenatal care (ANC) at The National Ribat University Hospital in Khartoum State in 2019 https://amphysiol.com/index.php/amp/article/view/v4i4.28248 <p>Pregnancy involves remarkable physiological changes and the functional impact of pregnancy on the kidney physiology is widespread involving practically all aspects of kidney functions. The aim of this study was to evaluate the renal functions in Sudanese healthy pregnant ladies during different trimesters. A cross sectional study was carried out during July to October 2019 on Sudanese healthy pregnant ladies attending antenatal care at the National Ribat University Hospital in Khartoum State. The study covered 60 healthy pregnant ladies (20 for each trimester). The purpose of the study was explained to all participants and they were assessed after taking their consent. Blood pressure (BP) and body mass index (BMI) were measured by standard techniques. A sample of five ml venous blood was taken in a suitable blood container for measurement of urea and creatinine using a fully automated Mindray BS-300 Chemistry Analyzer (Mindray Bio-Medical Electronics Co., Ltd., Shenzhen, China). The data was analyzed using SPSS version 25 (IBM SPSS Inc., Chicago, IL, USA), t-test was used to compare the statistical significant (p value ? 0.05 was considered statistical significant). The mean age of participants was 26.6±5.3 years with the range of 18-37 years. The mean BMI was 25.7±3.6 with the range of 18-31. The mean urea in the first, second and third trimester was 13.4, 13.9 and 13.2 mg/dl respectively with no statistically significant variation. The mean creatinine in the first, second and third trimester was 0.6, 0.6 and 0.5 mg/dl respectively with no statistically significant variation. To conclude, there was no significant variation of serum urea and creatinine during three trimesters of pregnancy in healthy pregnant women.</p> Ibrahim Abdelrhim Ali Elham Bourai Hassan Khalid S. Elhassan Copyright (c) 2020 Quench Academy of Medical Education and Research (QAMER) https://creativecommons.org/licenses/by/4.0 2021-01-15 2021-01-15 5 3 24 28 10.23921/amp.2020v4i4.28248 Emergence of MIS-C in COVID-19 pandemic https://amphysiol.com/index.php/amp/article/view/v4i3.14465 Mehnaaz Sameera Arifuddin Copyright (c) 2020 Quench Academy of Medical Education and Research (QAMER) https://creativecommons.org/licenses/by/4.0 2021-01-15 2021-01-15 5 3 22 23 10.23921/amp.2020v4i3.14465