Target with-in target

Aiming to break therapeutic mediocrity

Authors

DOI:

https://doi.org/10.23921/amp.2018v2i1.275951

Keywords:

Molecular imaging, Molecular target, Pharmaco-therapeutics, Receptors, Target exposure

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Author Biography

Mohammed Abdul Hannan Hazari, Deccan College of Medical Sciences

Professor & Head, Department of Physiology

References

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<li>Bremer C. Molecular targets. In: Baert AL (ed) Encyclopedia of Diagnostic Imaging. New York: Springer Berlin Heidelberg, pp.1154-55, 2008.</li>
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<li>Molecular imaging. Available from: <a href="https://en.wikipedia.org/wiki/Molecular_imaging" target="_blank">https://en.wikipedia.org/wiki/Molecular_imaging</a> (Last accessed August 16, 2017)</li>
<li>Verdine GL, Hilinski GJ. Stapled peptides for intracellular drug targets. Methods Enzymol. 2012; 503:3-33. <a title="PMID" href="https://www.ncbi.nlm.nih.gov/pubmed/22230563" target="_blank">[Pubmed]</a> <a title="DOI" href="https://doi.org/10.1016/B978-0-12-396962-0.00001-X" target="_blank">[Crossref]</a></li>
<li>Imming P, Sinning C, Meyer A. Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct; 5(10):821-34. <a title="PMID" href="https://www.ncbi.nlm.nih.gov/pubmed/17016423" target="_blank">[Pubmed]</a> <a title="DOI" href="https://doi.org/10.1038/nrd2132" target="_blank">[Crossref]</a></li>
<li>Eleven Biotherapeutics. Vicinium&trade; (VB4-845): Recombinant fusion protein in clinical development for the treatment of high-grade non-muscle invasive bladder cancer. Available from: <a href="http://www.elevenbio.com/pipeline/vicinium.html" target="_blank">http://www.elevenbio.com/pipeline/vicinium.html</a> (Last accessed August 21, 2017)</li>
<li>Cardinale A, Biocca S. The potential of intracellular antibodies for therapeutic targeting of protein-misfolding diseases. Trends Mol Med. 2008 Sep; 14(9):373-80. <a title="PMID" href="https://www.ncbi.nlm.nih.gov/pubmed/18693139" target="_blank">[Pubmed]</a> <a title="DOI" href="https://doi.org/10.1016/j.molmed.2008.07.004" target="_blank">[Crossref]</a></li>
<li>Reverdatto S, Burz DS, Shekhtman A. Peptide aptamers: development and applications. Curr Top Med Chem. 2015; 15(12):1082-101. <a title="PMID" href="https://www.ncbi.nlm.nih.gov/pubmed/25866267" target="_blank">[Pubmed]</a> <a title="DOI" href="https://doi.org/10.2174/1568026615666150413153143" target="_blank">[Crossref]</a></li>
<li>Mateus A, Gordon LJ, Wayne GJ, Almqvist H, Axelsson H, Seashore-Ludlow B, Treyer A, Matsson P, Lundb&auml;ck T, West A, Hann MM, Artursson P. Prediction of intracellular exposure bridges the gap between target- and cell-based drug discovery. Proc Natl Acad Sci U S A. 2017 Jul 25; 114(30):E6231-E6239. <a title="PMID" href="https://www.ncbi.nlm.nih.gov/pubmed/28701380" target="_blank">[Pubmed]</a> <a title="DOI" href="https://doi.org/10.1073/pnas.1701848114" target="_blank">[Crossref]</a></li>
</ol>
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Published

2018-03-31

How to Cite

1.
Hazari MAH. Target with-in target: Aiming to break therapeutic mediocrity. Ann Med Physiol [Internet]. 2018Mar.31 [cited 2022May22];2(1):1-2. Available from: https://amphysiol.com/index.php/amp/article/view/v2i1.275951

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