Annals of Medical Physiology http://amphysiol.com/index.php/amp <p><strong><span style="margin: 0px; line-height: 150%; font-family: 'Arial','sans-serif'; font-size: 12pt;">Annals of Medical Physiology</span></strong><span style="margin: 0px; line-height: 150%; font-family: 'Arial','sans-serif'; font-size: 12pt;"> (<em>Ann Med Physiol.</em>) is a double-blind peer-reviewed quarterly journal, published both online and in print version, aims to provide the most complete and reliable source of information on current developments in the field of medical physiology. The emphasis will be on publishing quality research papers rapidly and keep freely available to researchers worldwide through </span><span style="margin: 0px; line-height: 150%; font-family: 'Arial','sans-serif'; font-size: 12pt;"><span style="color: #0000ff;">open access policy</span></span><span style="margin: 0px; line-height: 150%; font-family: 'Arial','sans-serif'; font-size: 12pt;">. <strong>Annals of Medical Physiology</strong> serves an important role by encouraging, fostering and promoting developments in various areas of medical physiology. This journal publishes reviews, original research articles, brief communications in all areas of medical physiology.</span></p> <p><strong><span style="margin: 0px; line-height: 150%; font-family: 'Arial','sans-serif'; font-size: 12pt;">Features:</span></strong></p> <ul type="disc"> <li class="show" style="margin: 0px 0px 8px; color: #000000; line-height: 150%; font-family: 'Arial','sans-serif'; font-size: 12pt; font-style: normal; font-weight: normal;"><span style="margin: 0px; line-height: 150%; font-family: 'Arial','sans-serif'; font-size: 12pt;">International quality</span></li> <li class="show" style="margin: 0px 0px 8px; color: #000000; line-height: 150%; font-family: 'Arial','sans-serif'; font-size: 12pt; font-style: normal; font-weight: normal;"><span style="margin: 0px; line-height: 150%; font-family: 'Arial','sans-serif'; font-size: 12pt;">Published quarterly (Jan-Mar, Apr-June, July-Sept, Oct-Dec)</span></li> <li class="show" style="margin: 0px 0px 8px; color: #000000; line-height: 150%; font-family: 'Arial','sans-serif'; font-size: 12pt; font-style: normal; font-weight: normal;"><span style="margin: 0px; line-height: 150%; font-family: 'Arial','sans-serif'; font-size: 12pt;">Fast acceptance and quick publication (Online first)</span></li> <li class="show" style="margin: 0px 0px 8px; color: #000000; line-height: 150%; font-family: 'Arial','sans-serif'; font-size: 12pt; font-style: normal; font-weight: normal;"><span style="margin: 0px; line-height: 150%; font-family: 'Arial','sans-serif'; font-size: 12pt;">Online manuscript submission</span></li> <li class="show" style="margin: 0px 0px 8px; color: #000000; line-height: 150%; font-family: 'Arial','sans-serif'; font-size: 12pt; font-style: normal; font-weight: normal;"><span style="margin: 0px; line-height: 115%; font-family: 'Arial','sans-serif'; font-size: 12pt;">Nominal publication charges</span></li> </ul> en-US <p>The authors warrants and represents that the submitted <strong>MANUSCRIPT</strong> is an original work and has not been published before in any form, and that it does not infringe upon any copyright or other right(s), that it does not contain infringing, libelous, obscene or other unlawful matter, that he/she is the sole and exclusive owner of the rights here-in conveyed to the Publisher, and that he/she has obtained the customary permission from the copyright owner or his legal representative whenever a text/passage from copyrighted material is quoted or a table or illustration from such material is used. The Author(s) will indemnify the Publisher for, and hold the Publisher harmless from any loss, expense or damage occasioned by any claim or suit by a third party for copyright infringement or arising out of any breach of the foregoing warranties as a result of publication of the Article. The Article shall be delivered to the Publisher free of copyright charges. In the event that the Article is not accepted and published by Publisher, this agreement becomes null and void.</p> editor@amphysiol.com (Dr. Mohammed Abdul Hannan Hazari) hannanhazari@qamer.org (Dr. Mohammed Abdul Hannan Hazari) Wed, 28 Nov 2018 00:00:00 -0500 OJS 3.1.0.1 http://blogs.law.harvard.edu/tech/rss 60 Variation in carotid-femoral pulse wave velocity, augmentation pressure and augmentation index during different phases of menstrual cycle http://amphysiol.com/index.php/amp/article/view/v2i3.10454 <p>Physiological variation of estrogen and progesterone during menstrual cycle is well known.&nbsp; They not only have an effect on blood pressure control, but also seem to have a role in regulating arterial compliance. This study was done to find out whether there are any changes in central arterial parameters during different phases of menstrual cycle. Thirty female&nbsp; subjects&nbsp; in the&nbsp; age&nbsp; group&nbsp; of&nbsp; 18-22&nbsp; years&nbsp; with&nbsp; normal,&nbsp; regular menstrual&nbsp; cycles&nbsp; participated in this prospective observational study at our teaching hospital. Anthropometric parameters were recorded.&nbsp; Blood pressure in all 4 limbs was recorded using cardiovascular risk analyzer-Periscope™ on Day 3<sup>rd</sup> to 5<sup>th</sup> (follicular phase), Day 12<sup>th</sup> to 14<sup>th</sup> (ovulation phase), Day 22<sup>nd</sup> to 24<sup>th</sup> (luteal phase) of their menstrual cycle. We collected blood samples during these three phases for estimation of estradiol and progesterone by ELISA technique. Analysis of variance and correlation statistics were done using SPSS 17.0 statistical software. No significant statistical changes were observed in systolic blood pressure, diastolic blood pressure, mean arterial pressure, pulse pressure, aortic systolic pressure, aortic diastolic pressure, aortic augmentation pressure, aortic index and pulse wave velocity during the three recorded phases of the menstrual cycle. There are many studies which correlate changes in peripheral artery blood pressure with different phases of menstrual cycle. But there is scarcity in data available which correlates central arterial pressures and arterial stiffness with natural hormonal variations in different phases of menstrual cycle. However, our results show that although there are subtle changes in blood pressure parameters along with estrogen and progesterone levels throughout the menstrual cycle, yet these were not statistically significant.</p> Nudrat Kahkashan, Mehnaaz Sameera Arifuddin, Mohammed Abdul Hannan Hazari, Safia Sultana, Farah Fatima, Syyeda Anees ##submission.copyrightStatement## http://creativecommons.org/licenses/by/4.0 http://amphysiol.com/index.php/amp/article/view/v2i3.10454 Wed, 28 Nov 2018 00:00:00 -0500 Hemorheology: Capturing the fluid dynamics of blood http://amphysiol.com/index.php/amp/article/view/v2i3.15965 Mohammed Abdul Hannan Hazari ##submission.copyrightStatement## http://creativecommons.org/licenses/by/4.0 http://amphysiol.com/index.php/amp/article/view/v2i3.15965 Wed, 28 Nov 2018 00:00:00 -0500 A comparative study on ABO blood group and fertility hormones in infertile women in Calabar, Southern Nigeria http://amphysiol.com/index.php/amp/article/view/v2i2.298656 <p>Infertility, a disorder of the reproductive system, is commonly linked to hormonal, pituitary, cervical, uterine, immunological or psychological factors. Besides these factors, it can also be idiopathic or unexplained. Hence, there is a need for more research to unravel the causes of the unexplained infertility. This work aimed at finding out whether there is any relationship between ABO blood group system and female infertility. The study design was cross-sectional. Three hundred women between 18 and 40 years attending fertility clinic at the University of Calabar Teaching Hospital, Calabar between 2011 and 2012 were recruited for this study. Serum progesterone, prolactin, follicle stimulating hormone (FSH), luteinizing hormone (LH) and estradiol were determined using Enzyme linked immunosorbent assay (ELISA) while ABO blood grouping was determined using the tube method. Statistical analysis was done using SPSS version 18. The confidence level was set at 95% where p-value less than 0.05 was considered statistically significant. The mean age of the women was 30.65 ± 5.47 years and the percentage distributions of the blood groups among the women were as follows: 24% A, 12% B, 4% AB and 60% O. The mean FSH levels of blood groups A and O individuals were significantly higher (p&lt;0.05) than that of groups B. However, there was no significant difference (p&gt;0.05) in the mean levels of progesterone, prolactin, LH and estradiol in the respective groups. From this study, 38% of the population had increased levels of progesterone, 58% and 18.7% had elevated prolactin and FSH levels respectively while 11.33% and 43.3% had reduced levels of LH and estradiol levels respectively. Though, there was high prevalence of hyperprolactinemia observed in this study, there was no strong association between ABO blood group and female infertility but, the increased FSH levels observed in blood groups A and O may be a potential link between blood group and infertility and therefore may be beneficial for further study.</p> Uwem Okon Akpan, Iya Eze Bassey, Nnenna Nkiruka Nwatu, Sunday Jeremiah Offor ##submission.copyrightStatement## http://creativecommons.org/licenses/by/4.0 http://amphysiol.com/index.php/amp/article/view/v2i2.298656 Sun, 01 Jul 2018 02:17:33 -0400 Nanophysiology: Real-time phenomenal perspective in biology http://amphysiol.com/index.php/amp/article/view/v2i2.302175 Mohammed Abdul Hannan Hazari ##submission.copyrightStatement## http://creativecommons.org/licenses/by/4.0 http://amphysiol.com/index.php/amp/article/view/v2i2.302175 Sun, 01 Jul 2018 01:45:58 -0400 Vitamin D status in medical students and risk factor analysis http://amphysiol.com/index.php/amp/article/view/v2i1.289803 <p>Vitamin D is finding increasing health implications beyond calcium homeostasis. Vitamin D deficiency is prevalent globally including India. Many asymptomatic individuals have hypovitaminosis implicating the need for intervention. The present study aimed at evaluating vitamin D levels among healthy medical students from southern India and its association with well-known risk factors. Hundred apparently healthy medical students between the age group of 18-25 years were recruited based on defined inclusion and exclusion criteria. A questionnaire form with details of sun exposure, tanning, milk intake, general health and drug history were obtained. Vitamin D levels were assessed by chemiluminescent immunoassay (CLIA). Vitamin D values were considered normal for 30-60 ng/ml, deficient for &lt;20 ng/ml and insufficient for levels between 21-29 ng/ml. Majority of the students (89%) had deficient 25-hydroxyvitamin D levels while 8% of the student had insufficient and 3% of the students had sufficient 25-hydroxyvitamin D levels. The mean 25-hydroxyvitamin D level was 14.01±6.20 ng/ml, median level was 12.95 ng/ml and ranged between 5.15 to 43.01 ng/ml. No statistically significant association was noted with sex, BMI, sun exposure, dietary intake or serum calcium levels. To conclude, vitamin D deficiency is highly prevalent in asymptomatic medical students and showed lack of relationship with the well-defined risk factors in literature prompting to look for newer risk factors in this country.</p> Vidya Sunil Joshi, Rahul Mandal ##submission.copyrightStatement## http://creativecommons.org/licenses/by/4.0 http://amphysiol.com/index.php/amp/article/view/v2i1.289803 Sat, 31 Mar 2018 06:12:23 -0400 Immediate and delayed effect of Ramadan fasting on spirometry parameters http://amphysiol.com/index.php/amp/article/view/v2i1.279619 <p>Fasting in the month of Ramadan is an obligatory duty for muslims. Researchers have investigated health benefits of fasting and reported conflicting results. The purpose of this study was to determine the immediate and delayed effects of Ramadan fasting on spirometric parameters. 50 apparently healthy young adults aged between 17-27 years, belonging to both genders who fast during the month of Ramadan were enrolled for the study. Spirometric recordings were done at three different time points. First: 5-10 days before the start of Ramadan (Pre-Ramadan); second: within 10 days of the beginning of Ramadan fasting (Ramadan); third: within 7 days of the end of Ramadan (Post-Ramadan). There were no statistically significant differences between the three phases with respect to tidal volume (TV), inspiratory reserve volume (IRV), expiratory reserve volume (ERV), forced vital capacity (FVC), forced expiratory volume in 1 sec (FEV1), FEV1/FVC, peak expiratory flow rate (PEFR) and forced expiratory flow 25% to 75% (FEF25-27). To conclude, Ramadan fasting does not have any significant effect on pulmonary function tests as assessed by spirometry. Hence, the diagnosis and prognosis of a respiratory disorder made on spirometry findings are reliable and need no error correction if an individual is fasting.</p> Adiba Sayeed, Mohammed Abdul Hannan Hazari, Mehnaaz Sameera Arifuddin ##submission.copyrightStatement## http://creativecommons.org/licenses/by/4.0 http://amphysiol.com/index.php/amp/article/view/v2i1.279619 Sat, 31 Mar 2018 06:01:09 -0400 Menarcheal age of blind girls http://amphysiol.com/index.php/amp/article/view/v2i1.277584 <p>Menarche is a developmental milestone. Age at which menarche is attained is highly variable and highly sensitive to a variety of internal and external forces like climatic conditions, physical and mental factors, nutrition and socio-economic status. Exposure to light and other visual cues may influence the pubertal changes. Menarcheal age (MA) of 110 blind girls was compared to that of 102 normal girls of same age group and of same area of residence. An advancement of 9 months in MA was seen in blind girls. Influence of light and other factors on menarche is discussed.</p> Kalanghot Padmanabhan Skandhan, Spandana Reddy, Amita Pandya, Sumangala Balakrishnan, Dayani Osuki, Jaya Vasudevan ##submission.copyrightStatement## http://creativecommons.org/licenses/by/4.0 http://amphysiol.com/index.php/amp/article/view/v2i1.277584 Sat, 31 Mar 2018 05:48:02 -0400 Target with-in target http://amphysiol.com/index.php/amp/article/view/v2i1.275951 Mohammed Abdul Hannan Hazari ##submission.copyrightStatement## http://creativecommons.org/licenses/by/4.0 http://amphysiol.com/index.php/amp/article/view/v2i1.275951 Sat, 31 Mar 2018 00:00:00 -0400 Prevalence of anemia in geriatric population of Kashmir: A hospital based study http://amphysiol.com/index.php/amp/article/view/v1i1.262231 <p>Anemia is a common concern in geriatric age group in developing countries. The purpose of this study was to identify the common causes and types of anemia in elderly patients in educationally backward region with limited access to quality health care. This was an observational study was done in Shri Maharaja Hari Singh (SMHS) Hospital of Government Medical College Srinagar, over a period of two years. 2000 patients above 60 years of age attending the outpatient clinic were screened for anemia based on WHO criteria. A random and non-consecutive selection of 100 anemic patients was done to study the morphological type and cause of anemia. 1160 (58%) patients were males and 840 (42%) were females.&nbsp; Total 812 out of 840 (96.67%) females and 738 out of 1160 (63.62%) males were found to be anemic. Maximum numbers of anemic patients were found in the age group 60-69 years. Mean age was 74.5 years. All the types of anemia based on peripheral smear were evident, normocytic being the commonest constituting 77.5%, followed by microcytic hypochromic 11.1%, macrocytic 7.05% and dimorphic 4.35%. 21% were lost to follow up and almost one fourth of the patients (24%) needed further evaluation before labelling them as having anemia due to old age. The common causes of anemia noted were gastrointestinal malignancy (31%), renal insufficiency (15%) and tuberculosis (9%). The inability to evaluate anemia in elderly individuals can lead to delay in the diagnosis of treatable as well as threatening disease conditions.</p> Nazia Hilal, Azher Mushtaq ##submission.copyrightStatement## http://creativecommons.org/licenses/by/4.0 http://amphysiol.com/index.php/amp/article/view/v1i1.262231 Fri, 14 Apr 2017 00:00:00 -0400 Hematological parameters are acutely effected by cement dust exposure in construction workers http://amphysiol.com/index.php/amp/article/view/v1i1.263312 <p>Cement dust poses an occupational hazard causing respiratory (owing to its inhalation), dermatological, ocular and hematological problems. The purpose of the current study was to evaluate the effect of occupational exposure of cement dust on hematological parameters in construction workers. Apparently healthy sixty five (65) adult male construction workers aged 25-50 years participated in this study. Three (3.0) ml venous blood samples were collected from each participant for hematological analysis at two different time points, one at 8 AM and second at 4 PM at the end of work shift. Differences in means and test of significance were calculated using paired Student’s t-test. The results revealed that post shift samples showed statistically significant increase (p&lt;0.05) in mean total leukocyte count (TLC), lymphocyte %, monocyte % and eosinophil % &nbsp;and statistically significant decrease (p&lt;0.05) in mean hemoglobin, red blood cell (RBC) count, packed cell volume (PCV) and platelet count. The present study confirms that hematological parameters are significantly effected in construction workers which may be attributed to the work atmosphere predominated with cement dust.</p> Ayesha Farheen, Mohammed Abdul Hannan Hazari, Farisa Khatoon, Fareen Sultana, Sanam Maria Qudsiya ##submission.copyrightStatement## http://creativecommons.org/licenses/by/4.0 http://amphysiol.com/index.php/amp/article/view/v1i1.263312 Thu, 13 Apr 2017 00:00:00 -0400